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PF-3758309 hydrochloride

CAS No. 1279034-84-2

PF-3758309 hydrochloride ( —— )

Catalog No. M17237 CAS No. 1279034-84-2

PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PF-3758309 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity.
  • Description
    PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PAK4 inhibitor PF-03758309 binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PAK4; PAK1; PAK6; PAK5; PAK3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1279034-84-2
  • Formula Weight
    527.08
  • Molecular Formula
    C25H31ClN8OS
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    Cl.CN(C)C[C@@H](NC(=O)N1Cc2c(n[nH]c2Nc2nc(C)nc3ccsc23)C1(C)C)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Briz V, Baudry M.2014 Feb 25;5:22. doi: 10.3389/fendo.2014.00022. eCollection 2014. PubMed PMID: 24611062; PubMed Central PMCID: PMC3933789.
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